Curis Hedgehog and Beyond --plus multi-targeting cancer inhibitors

Human Invasive Prostate Cancer Cells

Altogether, these observations suggest that EGFR and sonic hedgehog cascades may represent the potential therapeutic targets of great clinical interest to eradicate the total prostate cancer cell mass and improve the current docetaxel-based therapies against locally advanced and invasive prostate cancers, and thereby prevent metastases and disease relapse.
http://www.ncbi.nlm.nih.gov/pubmed/20179163

origin of basal cell carcinoma

http://www.ncbi.nlm.nih.gov/pubmed/20154679

Increased expression of the hedgehog signaling pathway in pediatric ...