" Part of investing is not being afraid to go against the crowd. I've been following curis for a long time, and the news out yesterday re: their clinical trials was disappoointing, but by no means does it refute the potential efficacy that the hedgehog pathway can have. I consider the "preliminary" results to be one strike, in one inning, of a long baseball game. All selling today is on speculation that the drug will fail. With the stock down this much, I think it's worth taking a risk that the drug might actually succeed. How's that for a spin job! I'm long at 2.36 today (that's right, i actually got it one penny above the low - call me lucky). "