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 | Revisiting the biological roles of PAI2 (SERPINB2) in cance |  |
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Tumour expression of the urokinase plasminogen activator correlates with invasive capacity. Consequently, inhibition of this serine protease by physiological inhibitors should decrease invasion and metastasis. However, of the two main urokinase inhibitors, high tumour levels of the type 1 inhibitor actually promote tumour progression, whereas Read more... Source: Nature Reviews Cancer |
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 | Revisiting the biological roles of PAI2 (SERPINB2) in cance | |
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