SUMO amplifies TGF-β signalling

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SUMO amplifies TGF-β signalling
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Post Posted: Mon Jun 02, 2008 10:07 am Reply with quote


Transforming growth factor-β (TGF-β) stimulates phosphorylation of TGF-β type I receptor. This receptor is now shown to be sumoylated, leading to enhanced activation and modulation of the downstream Smad signalling pathway.

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Source: Nature Cell Biology
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SUMO amplifies TGF-β signalling
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