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 | Targeting the oncogene and kinome chaperone CDC37 |  |
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CDC37 is a molecular chaperone that physically stabilizes the catalytic domains found in protein kinases and is therefore a wide-spectrum regulator of protein phosphorylation. It is also an overexpressed oncoprotein that mediates carcinogenesis by stabilizing the compromised structures of mutant and/or overexpressed oncogenic kinases. Recent Read more... Source: Nature Reviews Cancer |
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 | Targeting the oncogene and kinome chaperone CDC37 | |
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