Tumorigenesis: Some HIFs are more equal than others

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Tumorigenesis: Some HIFs are more equal than others
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Loss of function of the von Hippel–Lindau tumour suppressor VHL, which results in activation of the transcription factors hypoxia-inducible factor 1 (HIF1) and HIF2, is associated with development of highly vascularized tumours in multiple organs. New research from Rankin and colleagues, published in Oncogene

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Source: Nature Reviews Cancer
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Tumorigenesis: Some HIFs are more equal than others
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